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In addition, the indole core is substituted at R3 with a carbonyl group that's also bonded to the napthalene moeity. Napthalene is actually a bicyclic framework of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it for a ketone. JWH-018 can be an analog of THJ-018, in which the Main indazole composition is substituted having an indole foundation. Pharmacology
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